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Inhibition of αvβ3 integrin impairs adhesion and uptake of tumor-derived small extracellular vesicles

BACKGROUND: Extracellular vesicles (EVs) are lipid-bound particles that are naturally released from cells and mediate cell-cell communication. Integrin adhesion receptors are enriched in small EVs (SEVs) and SEV-carried integrins have been shown to promote cancer cell migration and to mediate organ-...

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Detalles Bibliográficos
Autores principales: Altei, Wanessa F., Pachane, Bianca C., dos Santos, Patty K., Ribeiro, Lígia N. M., Sung, Bong Hwan, Weaver, Alissa M., Selistre-de-Araújo, Heloisa S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7520983/
https://www.ncbi.nlm.nih.gov/pubmed/32988382
http://dx.doi.org/10.1186/s12964-020-00630-w