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Inhibition of αvβ3 integrin impairs adhesion and uptake of tumor-derived small extracellular vesicles
BACKGROUND: Extracellular vesicles (EVs) are lipid-bound particles that are naturally released from cells and mediate cell-cell communication. Integrin adhesion receptors are enriched in small EVs (SEVs) and SEV-carried integrins have been shown to promote cancer cell migration and to mediate organ-...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7520983/ https://www.ncbi.nlm.nih.gov/pubmed/32988382 http://dx.doi.org/10.1186/s12964-020-00630-w |