Cargando…
Inhibition of αvβ3 integrin impairs adhesion and uptake of tumor-derived small extracellular vesicles
BACKGROUND: Extracellular vesicles (EVs) are lipid-bound particles that are naturally released from cells and mediate cell-cell communication. Integrin adhesion receptors are enriched in small EVs (SEVs) and SEV-carried integrins have been shown to promote cancer cell migration and to mediate organ-...
Autores principales: | Altei, Wanessa F., Pachane, Bianca C., dos Santos, Patty K., Ribeiro, Lígia N. M., Sung, Bong Hwan, Weaver, Alissa M., Selistre-de-Araújo, Heloisa S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7520983/ https://www.ncbi.nlm.nih.gov/pubmed/32988382 http://dx.doi.org/10.1186/s12964-020-00630-w |
Ejemplares similares
-
Tumor heterogeneity and the dilemma of antioxidant therapies in cancer
por: Selistre-de-Araujo, Heloisa Sobreiro, et al.
Publicado: (2022) -
Recombinant RGD-disintegrin DisBa-01 blocks integrin α(v)β(3) and impairs VEGF signaling in endothelial cells
por: Danilucci, Taís M., et al.
Publicado: (2019) -
Small Extracellular Vesicles from Hypoxic Triple-Negative Breast Cancer Cells Induce Oxygen-Dependent Cell Invasion
por: Pachane, Bianca Cruz, et al.
Publicado: (2022) -
The Effects of αvβ3 Integrin Blockage in Breast Tumor and Endothelial Cells under Hypoxia In Vitro
por: Casali, Bruna C., et al.
Publicado: (2022) -
Metastasis inhibition in breast cancer by targeting cancer cell extravasation
por: Cominetti, Márcia R, et al.
Publicado: (2019)