Azithromycin and glucosamine may amplify the type 1 interferon response to RNA viruses in a complementary fashion

Previous research demonstrates that, in clinically relevant concentrations, azithromycin can boost the ability of RNA viruses to induce type 1 interferon by amplifying the expression and virally-mediated activation of MDA5. O-GlcNAcylation of MAVS, a down-stream target of MDA5, renders it more effec...

Descripción completa

Detalles Bibliográficos
Autores principales: DiNicolantonio, James J., Barroso-Aranda, Jorge, McCarty, Mark F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Federation of Immunological Societies. Published by Elsevier B.V. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521214/
https://www.ncbi.nlm.nih.gov/pubmed/33002511
http://dx.doi.org/10.1016/j.imlet.2020.09.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521214/
https://www.ncbi.nlm.nih.gov/pubmed/33002511
http://dx.doi.org/10.1016/j.imlet.2020.09.008

Ejemplares similares