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TLR9 deficiency alleviates doxorubicin‐induced cardiotoxicity via the regulation of autophagy

Doxorubicin is a commonly used anthracycline chemotherapeutic drug. Its application for treatment has been impeded by its cardiotoxicity as it is detrimental and fatal. DNA damage, cardiac inflammation, oxidative stress and cell death are the critical links in DOX‐induced myocardial injury. Previous...

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Detalles Bibliográficos
Autores principales: Guo, Zhen, Tang, Nan, Liu, Fang‐Yuan, Yang, Zheng, Ma, Shu‐Qing, An, Peng, Wu, Hai‐Ming, Fan, Di, Tang, Qi‐Zhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521247/
https://www.ncbi.nlm.nih.gov/pubmed/33140921
http://dx.doi.org/10.1111/jcmm.15719