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Silencing miR‐20a‐5p inhibits axonal growth and neuronal branching and prevents epileptogenesis through RGMa‐RhoA‐mediated synaptic plasticity

Epileptogenesis is a potential process. Mossy fibre sprouting (MFS) and synaptic plasticity promote epileptogenesis. Overexpression of repulsive guidance molecule a (RGMa) prevents epileptogenesis by inhibiting MFS. However, other aspects underlying the RGMa regulatory process of epileptogenesis hav...

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Detalles Bibliográficos
Autores principales: Feng, Yanyan, Duan, Chaojun, Luo, Zhaohui, Xiao, Wenbiao, Tian, Fafa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521253/
https://www.ncbi.nlm.nih.gov/pubmed/32779334
http://dx.doi.org/10.1111/jcmm.15677