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ST6Gal1 is up‐regulated and associated with aberrant IgA1 glycosylation in IgA nephropathy: An integrated analysis of the transcriptome

Galactose‐deficient IgA1 (Gd‐IgA1) plays a crucial role in the development of Immunoglobulin A nephropathy (IgAN), however, the underlying pathogenic mechanisms driving Gd‐IgA1 production in B cells are not well understood. In this study, RNA‐seq analysis identified 337 down‐regulated and 405 up‐reg...

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Detalles Bibliográficos
Autores principales: Liu, Youxia, Wang, Fanghao, Zhang, Yaru, Jia, Junya, Yan, Tiekun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521275/
https://www.ncbi.nlm.nih.gov/pubmed/32677771
http://dx.doi.org/10.1111/jcmm.15664