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BDNF promoted osteoblast migration and fracture healing by up‐regulating integrin β1 via TrkB‐mediated ERK1/2 and AKT signalling

Brain‐derived neurotrophic factor (BDNF) has been reported to participate in fracture healing, whereas the mechanism is still unclear. Since osteoblast migration is important for fracture healing, investigating effects of BDNF on osteoblasts migration may help to reveal its mechanism. Here, MC3T3‐E1...

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Detalles Bibliográficos
Autores principales: Zhang, Zitao, Hu, Polu, Wang, Zhen, Qiu, Xusheng, Chen, Yixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521296/
https://www.ncbi.nlm.nih.gov/pubmed/32803867
http://dx.doi.org/10.1111/jcmm.15704