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Honokiol ameliorates angiotensin II‐induced hypertension and endothelial dysfunction by inhibiting HDAC6‐mediated cystathionine γ‐lyase degradation

Hypertension and endothelial dysfunction are associated with various cardiovascular diseases. Hydrogen sulphide (H(2)S) produced by cystathionine γ‐lyase (CSE) promotes vascular relaxation and lowers hypertension. Honokiol (HNK), a natural compound in the Magnolia plant, has been shown to retain mul...

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Detalles Bibliográficos
Autores principales: Chi, Zhexi, Le, Truc Phan Hoang, Lee, Sang Ki, Guo, Erling, Kim, Dongsoo, Lee, Sanha, Seo, Seung‐Yong, Lee, Sook Young, Kim, Jae Hyung, Lee, Sang Yoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521302/
https://www.ncbi.nlm.nih.gov/pubmed/32755037
http://dx.doi.org/10.1111/jcmm.15686