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Hypermethylation of lncRNA MEG3 impairs chemosensitivity of breast cancer cells

BACKGROUND: Chemoresistance posed a barrier to successful treatment of breast cancer (BC), and lncRNA MEG3 has been documented to implicate in BC development. However, whether MEG3 methylation, which led to low MEG3 expression, was relevant to BC progression and chemoresistance remained uncertain. M...

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Detalles Bibliográficos
Autores principales: Li, Hongchang, Wang, Puhua, Liu, Jiazhe, Liu, Weiyan, Wu, Xubo, Ding, Junbin, Kang, Jie, Li, Jindong, Lu, Jingfeng, Pan, Gaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521317/
https://www.ncbi.nlm.nih.gov/pubmed/32618397
http://dx.doi.org/10.1002/jcla.23369