Cargando…

Hypomethylation of the promoter region drives ectopic expression of TMEM244 in Sézary cells

Sézary syndrome (SS) is an aggressive form of cutaneous T‐cell lymphoma (CTCL) characterized by the presence of circulating malignant CD4+ T cells (Sézary cells) with many complex changes in the genome, transcriptome and epigenome. Epigenetic dysregulation seems to have an important role in the deve...

Descripción completa

Detalles Bibliográficos
Autores principales: Iżykowska, Katarzyna, Rassek, Karolina, Żurawek, Magdalena, Nowicka, Karina, Paczkowska, Julia, Ziółkowska‐Suchanek, Iwona, Podralska, Marta, Dzikiewicz‐Krawczyk, Agnieszka, Joks, Monika, Olek‐Hrab, Karolina, Giefing, Maciej, Przybylski, Grzegorz K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521334/
https://www.ncbi.nlm.nih.gov/pubmed/32794659
http://dx.doi.org/10.1111/jcmm.15729