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Reversing Parkinson Disease Model with in situ Converted Nigral Neurons
Parkinson disease is characterized by loss of dopamine neurons in the substantia nigra1. Similar to other major neurodegenerative disorders, no disease-modifying treatment exists. While most treatment strategies aim to prevent neuronal loss or protect vulnerable neuronal circuits, a potential altern...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521455/ https://www.ncbi.nlm.nih.gov/pubmed/32581380 http://dx.doi.org/10.1038/s41586-020-2388-4 |