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Reversing Parkinson Disease Model with in situ Converted Nigral Neurons

Parkinson disease is characterized by loss of dopamine neurons in the substantia nigra1. Similar to other major neurodegenerative disorders, no disease-modifying treatment exists. While most treatment strategies aim to prevent neuronal loss or protect vulnerable neuronal circuits, a potential altern...

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Detalles Bibliográficos
Autores principales: Qian, Hao, Kang, Xinjiang, Hu, Jing, Zhang, Dongyang, Liang, Zhengyu, Meng, Fan, Zhang, Xuan, Xue, Yuanchao, Maimon, Roy, Dowdy, Steven F., Devaraj, Neal K., Zhou, Zhuan, Mobley, William C., Cleveland, Don W., Fu, Xiang-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521455/
https://www.ncbi.nlm.nih.gov/pubmed/32581380
http://dx.doi.org/10.1038/s41586-020-2388-4