Celastrol regulates bone marrow mesenchymal stem cell fate and bone-fat balance in osteoporosis and skeletal aging by inducing PGC-1α signaling

Celastrol has recently been identified as a prospective new treatment for obesity and several metabolic complications. However, the effect of Celastrol in osteoporosis (OP) remains unknown. In this study, we demonstrated that Celastrol promotes osteoblast differentiation and prevents adipocyte diffe...

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Detalles Bibliográficos
Autores principales: Li, Li, Wang, Bing, Li, Yawei, Li, Lei, Dai, Yuliang, Lv, Guohua, Wu, Pengfei, Li, Pengzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521495/
https://www.ncbi.nlm.nih.gov/pubmed/32723973
http://dx.doi.org/10.18632/aging.103590

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521495/
https://www.ncbi.nlm.nih.gov/pubmed/32723973
http://dx.doi.org/10.18632/aging.103590

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