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A novel hypoxic tumor microenvironment signature for predicting the survival, progression, immune responsiveness and chemoresistance of glioblastoma: a multi-omic study

The hypoxic tumor microenvironment (TME) was reported to promote the aggressive phenotype, progression, recurrence, and chemoresistance of glioblastoma (GBM). We developed and validated a hypoxia gene signature for individualized prognostic prediction in GBM patients. In total, 259 GBM-specific hypo...

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Detalles Bibliográficos
Autores principales: Wang, Zihao, Gao, Lu, Guo, Xiaopeng, Wang, Yaning, Wang, Yu, Ma, Wenbin, Guo, Yi, Xing, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521504/
https://www.ncbi.nlm.nih.gov/pubmed/32857727
http://dx.doi.org/10.18632/aging.103626