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Parietal epithelial cell differentiation to a podocyte fate in the aged mouse kidney
Healthy aging is typified by a progressive and absolute loss of podocytes over the lifespan of animals and humans. To test the hypothesis that a subset of glomerular parietal epithelial cell (PEC) progenitors transition to a podocyte fate with aging, dual reporter PEC-rtTA|LC1|tdTomato|Nphs1-FLPo|FR...
Autores principales: | Kaverina, Natalya V., Eng, Diana G., Miner, Jeffrey H., Pippin, Jeffrey W., Shankland, Stuart J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521511/ https://www.ncbi.nlm.nih.gov/pubmed/32858527 http://dx.doi.org/10.18632/aging.103788 |
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