DUSP4 directly deubiquitinates and stabilizes Smad4 protein, promoting proliferation and metastasis of colorectal cancer cells

Colorectal cancer is a common health-threatening tumor within the gastrointestinal tract. The aim of this study was to test the biological role of DUSP4 in colorectal cancer cells. In our study, DUSP4 overexpression-treated HCT116 cells and DUSP4 knockdown-treated SW480 cells were selected to perfor...

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Detalles Bibliográficos
Autores principales: Xu, Weifeng, Chen, Beibei, Ke, Dianshan, Chen, Xiaobing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521518/
https://www.ncbi.nlm.nih.gov/pubmed/32897241
http://dx.doi.org/10.18632/aging.103823

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521518/
https://www.ncbi.nlm.nih.gov/pubmed/32897241
http://dx.doi.org/10.18632/aging.103823

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