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Metformin suppresses Nrf2-mediated chemoresistance in hepatocellular carcinoma cells by increasing glycolysis

The diabetes drug metformin has recently been shown to possess anti-cancer properties when used with other chemotherapeutic drugs. However, detailed mechanisms by which metformin improves cancer treatment are poorly understood. Here we provide evidence in HepG2 hepatocellular carcinoma cells that me...

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Detalles Bibliográficos
Autores principales: Cai, Liangyu, Jin, Xin, Zhang, Jiannan, Li, Le, Zhao, Jinfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521529/
https://www.ncbi.nlm.nih.gov/pubmed/32927432
http://dx.doi.org/10.18632/aging.103777