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Mitophagy impairment is involved in sevoflurane-induced cognitive dysfunction in aged rats

Postoperative cognitive dysfunction (POCD) is frequently observed in elderly patients following anesthesia, but its pathophysiological mechanisms have not been fully elucidated. Sevoflurane was reported to repress autophagy in aged rat neurons; however, the role of mitophagy, which is crucial for th...

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Detalles Bibliográficos
Autores principales: Chen, Yeru, Zhang, Piao, Lin, Xianyi, Zhang, Huan, Miao, Jiamin, Zhou, Youfa, Chen, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521530/
https://www.ncbi.nlm.nih.gov/pubmed/32903215
http://dx.doi.org/10.18632/aging.103673