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Mitophagy impairment is involved in sevoflurane-induced cognitive dysfunction in aged rats
Postoperative cognitive dysfunction (POCD) is frequently observed in elderly patients following anesthesia, but its pathophysiological mechanisms have not been fully elucidated. Sevoflurane was reported to repress autophagy in aged rat neurons; however, the role of mitophagy, which is crucial for th...
Autores principales: | Chen, Yeru, Zhang, Piao, Lin, Xianyi, Zhang, Huan, Miao, Jiamin, Zhou, Youfa, Chen, Gang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521530/ https://www.ncbi.nlm.nih.gov/pubmed/32903215 http://dx.doi.org/10.18632/aging.103673 |
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