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A Switch in p53 Dynamics Marks Cells That Escape from DSB-Induced Cell Cycle Arrest

Cellular responses to stimuli can evolve over time, resulting in distinct early and late phases in response to a single signal. DNA damage induces a complex response that is largely orchestrated by the transcription factor p53, whose dynamics influence whether a damaged cell will arrest and repair t...

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Detalles Bibliográficos
Autores principales: Tsabar, Michael, Mock, Caroline S., Venkatachalam, Veena, Reyes, Jose, Karhohs, Kyle W., Oliver, Trudy G., Regev, Aviv, Jambhekar, Ashwini, Lahav, Galit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521664/
https://www.ncbi.nlm.nih.gov/pubmed/32755587
http://dx.doi.org/10.1016/j.celrep.2020.107995