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A Switch in p53 Dynamics Marks Cells That Escape from DSB-Induced Cell Cycle Arrest
Cellular responses to stimuli can evolve over time, resulting in distinct early and late phases in response to a single signal. DNA damage induces a complex response that is largely orchestrated by the transcription factor p53, whose dynamics influence whether a damaged cell will arrest and repair t...
Autores principales: | Tsabar, Michael, Mock, Caroline S., Venkatachalam, Veena, Reyes, Jose, Karhohs, Kyle W., Oliver, Trudy G., Regev, Aviv, Jambhekar, Ashwini, Lahav, Galit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521664/ https://www.ncbi.nlm.nih.gov/pubmed/32755587 http://dx.doi.org/10.1016/j.celrep.2020.107995 |
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