Protocol for In Vivo Evaluation and Use of Destabilizing Domains in the Eye, Liver, and Beyond

Destabilizing domains (DDs) have been used successfully to conditionally control the abundance of proteins of interest (POIs) in a small-molecule-dependent manner in mice, worms (Caenorhabditis elegans), and Drosophila. However, development of such systems must account for delivery of the DD-POIs to...

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Detalles Bibliográficos
Autores principales: Ramadurgum, Prerana, Daniel, Steffi, Hulleman, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521670/
https://www.ncbi.nlm.nih.gov/pubmed/32995756
http://dx.doi.org/10.1016/j.xpro.2020.100094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521670/
https://www.ncbi.nlm.nih.gov/pubmed/32995756
http://dx.doi.org/10.1016/j.xpro.2020.100094

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