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Protocol for In Vivo Evaluation and Use of Destabilizing Domains in the Eye, Liver, and Beyond
Destabilizing domains (DDs) have been used successfully to conditionally control the abundance of proteins of interest (POIs) in a small-molecule-dependent manner in mice, worms (Caenorhabditis elegans), and Drosophila. However, development of such systems must account for delivery of the DD-POIs to...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521670/ https://www.ncbi.nlm.nih.gov/pubmed/32995756 http://dx.doi.org/10.1016/j.xpro.2020.100094 |