Discovering functional sequences with RELICS, an analysis method for CRISPR screens

CRISPR screens are a powerful technology for the identification of genome sequences that affect cellular phenotypes such as gene expression, survival, and proliferation. By targeting non-coding sequences for perturbation, CRISPR screens have the potential to systematically discover novel functional...

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Detalles Bibliográficos
Autores principales: Fiaux, Patrick C., Chen, Hsiuyi V., Chen, Poshen B., Chen, Aaron R., McVicker, Graham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521704/
https://www.ncbi.nlm.nih.gov/pubmed/32936799
http://dx.doi.org/10.1371/journal.pcbi.1008194

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521704/
https://www.ncbi.nlm.nih.gov/pubmed/32936799
http://dx.doi.org/10.1371/journal.pcbi.1008194

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