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Novel cytokinetic ring components drive negative feedback in cortical contractility

Actomyosin cortical contractility drives many cell shape changes including cytokinetic furrowing. While positive regulation of contractility is well characterized, counterbalancing negative regulation and mechanical brakes are less well understood. The small GTPase RhoA is a central regulator, activ...

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Detalles Bibliográficos
Autores principales: Bell, Kathryn Rehain, Werner, Michael E., Doshi, Anusha, Cortes, Daniel B., Sattler, Adam, Vuong-Brender, Thanh, Labouesse, Michel, Maddox, Amy Shaub
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521795/
https://www.ncbi.nlm.nih.gov/pubmed/32491957
http://dx.doi.org/10.1091/mbc.E20-05-0304