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Nek8445, a protein kinase required for microtubule regulation and cytokinesis in Giardia lamblia

Giardia has 198 Nek kinases whereas humans have only 11. Giardia has a complex microtubule cytoskeleton that includes eight flagella and several unique microtubule arrays that are utilized for parasite attachment and facilitation of rapid mitosis and cytokinesis. The need to regulate these structure...

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Detalles Bibliográficos
Autores principales: Hennessey, Kelly M., Alas, Germain C. M., Rogiers, Ilse, Li, Renyu, Merritt, Ethan A., Paredez, Alexander R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521801/
https://www.ncbi.nlm.nih.gov/pubmed/32459558
http://dx.doi.org/10.1091/mbc.E19-07-0406