Cargando…
Nek8445, a protein kinase required for microtubule regulation and cytokinesis in Giardia lamblia
Giardia has 198 Nek kinases whereas humans have only 11. Giardia has a complex microtubule cytoskeleton that includes eight flagella and several unique microtubule arrays that are utilized for parasite attachment and facilitation of rapid mitosis and cytokinesis. The need to regulate these structure...
Autores principales: | Hennessey, Kelly M., Alas, Germain C. M., Rogiers, Ilse, Li, Renyu, Merritt, Ethan A., Paredez, Alexander R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521801/ https://www.ncbi.nlm.nih.gov/pubmed/32459558 http://dx.doi.org/10.1091/mbc.E19-07-0406 |
Ejemplares similares
-
Identification and Validation of Small-Gatekeeper Kinases as Drug Targets in Giardia lamblia
por: Hennessey, Kelly M., et al.
Publicado: (2016) -
Screening of the Pathogen Box for inhibitors with dual efficacy against Giardia lamblia and Cryptosporidium parvum
por: Hennessey, Kelly M., et al.
Publicado: (2018) -
A cell-cycle–dependent GARP-like transcriptional repressor regulates the initiation of differentiation in Giardia lamblia
por: Shih, Han-Wei, et al.
Publicado: (2022) -
A polo-like kinase modulates cytokinesis and flagella biogenesis in Giardia lamblia
por: Park, Eun-Ah, et al.
Publicado: (2021) -
14-3-3 Regulates Actin Filament Formation in the Deep-Branching Eukaryote Giardia lamblia
por: Krtková, Jana, et al.
Publicado: (2017)