Glutamate dehydrogenase (Gdh2)-dependent alkalization is dispensable for escape from macrophages and virulence of Candida albicans

Candida albicans cells depend on the energy derived from amino acid catabolism to induce and sustain hyphal growth inside phagosomes of engulfing macrophages. The concomitant deamination of amino acids is thought to neutralize the acidic microenvironment of phagosomes, a presumed requisite for survi...

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Detalles Bibliográficos
Autores principales: Silao, Fitz Gerald S., Ryman, Kicki, Jiang, Tong, Ward, Meliza, Hansmann, Nicolas, Molenaar, Chris, Liu, Ning-Ning, Chen, Changbin, Ljungdahl, Per O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521896/
https://www.ncbi.nlm.nih.gov/pubmed/32936835
http://dx.doi.org/10.1371/journal.ppat.1008328

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521896/
https://www.ncbi.nlm.nih.gov/pubmed/32936835
http://dx.doi.org/10.1371/journal.ppat.1008328

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