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COVID-19 Patients Upregulate Toll-like Receptor 4-mediated Inflammatory Signaling That Mimics Bacterial Sepsis

BACKGROUND: Observational studies of the ongoing coronavirus disease 2019 (COVID-19) outbreak suggest that a ‘cytokine storm’ is involved in the pathogenesis of severe illness. However, the molecular mechanisms underlying the altered pathological inflammation in COVID-19 are largely unknown. We repo...

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Detalles Bibliográficos
Autores principales: Sohn, Kyung Mok, Lee, Sung-Gwon, Kim, Hyeon Ji, Cheon, Shinhyea, Jeong, Hyeongseok, Lee, Jooyeon, Kim, In Soo, Silwal, Prashanta, Kim, Young Jae, Paik, Seungwha, Chung, Chaeuk, Park, Chungoo, Kim, Yeon-Sook, Jo, Eun-Kyeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521960/
https://www.ncbi.nlm.nih.gov/pubmed/32989935
http://dx.doi.org/10.3346/jkms.2020.35.e343