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Rabphilin involvement in filtration and molecular uptake in Drosophila nephrocytes suggests a similar role in human podocytes

Drosophila nephrocytes share functional, structural and molecular similarities with human podocytes. It is known that podocytes express the rabphilin 3A (RPH3A)-RAB3A complex, and its expression is altered in mouse and human proteinuric disease. Furthermore, we previously identified a polymorphism t...

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Detalles Bibliográficos
Autores principales: Selma-Soriano, Estela, Llamusi, Beatriz, Fernández-Costa, Juan Manuel, Ozimski, Lauren Louise, Artero, Rubén, Redón, Josep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522021/
https://www.ncbi.nlm.nih.gov/pubmed/32680845
http://dx.doi.org/10.1242/dmm.041509