Cercosporamide inhibits bone morphogenetic protein receptor type I kinase activity in zebrafish

Zebrafish models are well-established tools for investigating the underlying mechanisms of diseases. Here, we identified cercosporamide, a metabolite from the fungus Ascochyta aquiliqiae, as a potent bone morphogenetic protein receptor (BMPR) type I kinase inhibitor through a zebrafish embryo phenot...

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Detalles Bibliográficos
Autores principales: Hoeksma, Jelmer, van der Zon, Gerard C. M., ten Dijke, Peter, den Hertog, Jeroen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522027/
https://www.ncbi.nlm.nih.gov/pubmed/32820031
http://dx.doi.org/10.1242/dmm.045971

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522027/
https://www.ncbi.nlm.nih.gov/pubmed/32820031
http://dx.doi.org/10.1242/dmm.045971

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