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Evaluation of therapeutic efficacy of (211)At-labeled farletuzumab in an intraperitoneal mouse model of disseminated ovarian cancer

INTRODUCTION: Antibodies labeled with alpha-emitter astatine-211 have previously shown effective in intraperitoneal (i.p.) treatments of ovarian cancer. In the present work we explore the use of investigational farletuzumab, aimed at the folate receptor alpha. The aim was to evaluate the biodistribu...

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Detalles Bibliográficos
Autores principales: Palm, Stig, Bäck, Tom, Aneheim, Emma, Hallqvist, Andreas, Hultborn, Ragnar, Jacobsson, Lars, Jensen, Holger, Lindegren, Sture, Albertsson, Per
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522120/
https://www.ncbi.nlm.nih.gov/pubmed/32987283
http://dx.doi.org/10.1016/j.tranon.2020.100873