Cargando…
Evaluation of therapeutic efficacy of (211)At-labeled farletuzumab in an intraperitoneal mouse model of disseminated ovarian cancer
INTRODUCTION: Antibodies labeled with alpha-emitter astatine-211 have previously shown effective in intraperitoneal (i.p.) treatments of ovarian cancer. In the present work we explore the use of investigational farletuzumab, aimed at the folate receptor alpha. The aim was to evaluate the biodistribu...
Autores principales: | Palm, Stig, Bäck, Tom, Aneheim, Emma, Hallqvist, Andreas, Hultborn, Ragnar, Jacobsson, Lars, Jensen, Holger, Lindegren, Sture, Albertsson, Per |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522120/ https://www.ncbi.nlm.nih.gov/pubmed/32987283 http://dx.doi.org/10.1016/j.tranon.2020.100873 |
Ejemplares similares
-
Realizing Clinical Trials with Astatine-211: The Chemistry Infrastructure
por: Lindegren, Sture, et al.
Publicado: (2020) -
Estimating the Risk for Secondary Cancer After Targeted α-Therapy with (211)At Intraperitoneal Radioimmunotherapy
por: Leidermark, Erik, et al.
Publicado: (2023) -
Therapeutic efficacy of α-radioimmunotherapy with different activity levels of the (213)Bi-labeled monoclonal antibody MX35 in an ovarian cancer model
por: Gustafsson-Lutz, Anna, et al.
Publicado: (2017) -
Astatine-211 based radionuclide therapy: Current clinical trial landscape
por: Albertsson, Per, et al.
Publicado: (2023) -
Pretargeted Alpha Therapy of Disseminated Cancer Combining Click Chemistry and Astatine-211
por: Timperanza, Chiara, et al.
Publicado: (2023)