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Spatial Transcriptomics Reveals Genes Associated with Dysregulated Mitochondrial Functions and Stress Signaling in Alzheimer Disease

Alzheimer disease (AD) is a devastating neurological disease associated with progressive loss of mental skills and cognitive and physical functions whose etiology is not completely understood. Here, our goal was to simultaneously uncover novel and known molecular targets in the structured layers of...

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Detalles Bibliográficos
Autores principales: Navarro, José Fernández, Croteau, Deborah L., Jurek, Aleksandra, Andrusivova, Zaneta, Yang, Beimeng, Wang, Yue, Ogedegbe, Benjamin, Riaz, Tahira, Støen, Mari, Desler, Claus, Rasmussen, Lene Juel, Tønjum, Tone, Galas, Marie-Christine, Lundeberg, Joakim, Bohr, Vilhelm A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522123/
https://www.ncbi.nlm.nih.gov/pubmed/33083725
http://dx.doi.org/10.1016/j.isci.2020.101556