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Hypothalamic and Cell-Specific Transcriptomes Unravel a Dynamic Neuropil Remodeling in Leptin-Induced and Typical Pubertal Transition in Female Mice

Epidemiological and genome-wide association studies (GWAS) have shown high correlation between childhood obesity and advance in puberty. Early age at menarche is associated with a series of morbidities, including breast cancer, cardiovascular diseases, type 2 diabetes, and obesity. The adipocyte hor...

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Detalles Bibliográficos
Autores principales: Han, Xingfa, Burger, Laura L., Garcia-Galiano, David, Sim, Seokmin, Allen, Susan J., Olson, David P., Myers, Martin G., Elias, Carol F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522126/
https://www.ncbi.nlm.nih.gov/pubmed/33083731
http://dx.doi.org/10.1016/j.isci.2020.101563