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Hypothalamic and Cell-Specific Transcriptomes Unravel a Dynamic Neuropil Remodeling in Leptin-Induced and Typical Pubertal Transition in Female Mice
Epidemiological and genome-wide association studies (GWAS) have shown high correlation between childhood obesity and advance in puberty. Early age at menarche is associated with a series of morbidities, including breast cancer, cardiovascular diseases, type 2 diabetes, and obesity. The adipocyte hor...
Autores principales: | Han, Xingfa, Burger, Laura L., Garcia-Galiano, David, Sim, Seokmin, Allen, Susan J., Olson, David P., Myers, Martin G., Elias, Carol F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522126/ https://www.ncbi.nlm.nih.gov/pubmed/33083731 http://dx.doi.org/10.1016/j.isci.2020.101563 |
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