Predicting binding sites from unbound versus bound protein structures

We present the application of seven binding-site prediction algorithms to a meticulously curated dataset of ligand-bound and ligand-free crystal structures for 304 unique protein sequences (2528 crystal structures). We probe the influence of starting protein structures on the results of binding-site...

Descripción completa

Detalles Bibliográficos
Autores principales: Clark, Jordan J., Orban, Zachary J., Carlson, Heather A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522209/
https://www.ncbi.nlm.nih.gov/pubmed/32985584
http://dx.doi.org/10.1038/s41598-020-72906-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522209/
https://www.ncbi.nlm.nih.gov/pubmed/32985584
http://dx.doi.org/10.1038/s41598-020-72906-7

Ejemplares similares