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In vivo Imaging With (18)F-FDG- and (18)F-Florbetaben-PET/MRI Detects Pathological Changes in the Brain of the Commonly Used 5XFAD Mouse Model of Alzheimer's Disease

Imaging biomarkers of Alzheimer's disease (AD) that are able to detect molecular changes in vivo and transgenic animal models mimicking AD pathologies are essential for the evaluation of new therapeutic strategies. Positron-emission tomography (PET) using either (18)F-Fluorodeoxyglucose ((18)F-...

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Detalles Bibliográficos
Autores principales: Franke, Timon N., Irwin, Caroline, Bayer, Thomas A., Brenner, Winfried, Beindorff, Nicola, Bouter, Caroline, Bouter, Yvonne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522218/
https://www.ncbi.nlm.nih.gov/pubmed/33043029
http://dx.doi.org/10.3389/fmed.2020.00529