Resveratrol stereoselectively affected (±)warfarin pharmacokinetics and enhanced the anticoagulation effect

Resveratrol (RVT) has various beneficial bioactivities and popularly used as a dietary supplement. RVT showed inhibitions on CYP1A2/2C9/3A4, breast cancer resistance protein (BCRP), and some conjugated metabolites of RVT also inhibited BCRP. (±)Warfarin, an anticoagulant for cardiovascular disease b...

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Detalles Bibliográficos
Autores principales: Huang, Tse-Yin, Yu, Chung-Ping, Hsieh, Yow-Wen, Lin, Shiuan-Pey, Hou, Yu-Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522226/
https://www.ncbi.nlm.nih.gov/pubmed/32985569
http://dx.doi.org/10.1038/s41598-020-72694-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522226/
https://www.ncbi.nlm.nih.gov/pubmed/32985569
http://dx.doi.org/10.1038/s41598-020-72694-0

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