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PRMT5-mediated methylation of YBX1 regulates NF-κB activity in colorectal cancer

The multifunctional protein Y-box binding protein 1 (YBX1), is a critical regulator of transcription and translation, and is widely recognized as an oncogenic driver in several solid tumors, including colorectal cancer (CRC). However, very little is known about the upstream or downstream factors tha...

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Detalles Bibliográficos
Autores principales: Hartley, Antja-Voy, Wang, Benlian, Mundade, Rasika, Jiang, Guanglong, Sun, Mengyao, Wei, Han, Sun, Steven, Liu, Yunlong, Lu, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522246/
https://www.ncbi.nlm.nih.gov/pubmed/32985589
http://dx.doi.org/10.1038/s41598-020-72942-3