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PRMT5-mediated methylation of YBX1 regulates NF-κB activity in colorectal cancer
The multifunctional protein Y-box binding protein 1 (YBX1), is a critical regulator of transcription and translation, and is widely recognized as an oncogenic driver in several solid tumors, including colorectal cancer (CRC). However, very little is known about the upstream or downstream factors tha...
Autores principales: | Hartley, Antja-Voy, Wang, Benlian, Mundade, Rasika, Jiang, Guanglong, Sun, Mengyao, Wei, Han, Sun, Steven, Liu, Yunlong, Lu, Tao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522246/ https://www.ncbi.nlm.nih.gov/pubmed/32985589 http://dx.doi.org/10.1038/s41598-020-72942-3 |
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