Upregulation of HIF1-α via an NF-κB/COX2 pathway confers proliferative dominance of HER2-negative ductal carcinoma in situ cells in response to inflammatory stimuli

There are data to suggest that some ductal carcinoma in situ (DCIS) may evolve through an evolutionary bottleneck, where minor clones susceptible to the imposed selective pressure drive disease progression. Here, we tested the hypothesis that an impact of the inflammatory environment on DCIS evoluti...

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Detalles Bibliográficos
Autores principales: Piasecka, Dominika, Braun, Marcin, Mieszkowska, Magdalena, Kowalczyk, Lukasz, Kopczynski, Janusz, Kordek, Radzislaw, Sadej, Rafal, Romanska, Hanna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2020
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522292/
https://www.ncbi.nlm.nih.gov/pubmed/32980776
http://dx.doi.org/10.1016/j.neo.2020.09.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522292/
https://www.ncbi.nlm.nih.gov/pubmed/32980776
http://dx.doi.org/10.1016/j.neo.2020.09.003

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