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Integrated molecular characterization reveals potential therapeutic strategies for pulmonary sarcomatoid carcinoma

Pulmonary sarcomatoid carcinoma (PSC) is a rare subtype of lung cancer with poor prognosis. Here, we perform multi-omics analysis of 56 PSC samples, 14 of which are microdissected to analyze intratumoral heterogeneity. We report the mutational landscape of PSC. The epithelial and sarcomatoid compone...

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Detalles Bibliográficos
Autores principales: Yang, Zhenlin, Xu, Jiachen, Li, Lin, Li, Renda, Wang, Yalong, Tian, Yanhua, Guo, Wei, Wang, Zhijie, Tan, Fengwei, Ying, Jianming, Jiao, Yuchen, Gao, Shugeng, Wang, Jie, Gao, Yibo, He, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522294/
https://www.ncbi.nlm.nih.gov/pubmed/32985499
http://dx.doi.org/10.1038/s41467-020-18702-3