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Inactivation of Pancreatic Stellate Cells by Exendin-4 Inhibits the Migration and Invasion of Pancreatic Cancer Cells

BACKGROUND: Pancreatic stellate cells (PSCs) are precursor cells of cancer-associated fibroblasts that promote tumor proliferation, invasion, and metastasis. The glucagon-like peptide-1 receptor agonist exendin-4 has been reported to exhibit anticancer effects against several tumor cells; however, t...

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Detalles Bibliográficos
Autores principales: Yan, Meizhu, Shen, Manru, Xu, Linfang, Huang, Jiying, He, Guijun, An, Min, Li, Xiaocui, Gao, Zhenjun, Meng, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522302/
https://www.ncbi.nlm.nih.gov/pubmed/33061431
http://dx.doi.org/10.2147/OTT.S259853