Cargando…

Inactivation of Pancreatic Stellate Cells by Exendin-4 Inhibits the Migration and Invasion of Pancreatic Cancer Cells

BACKGROUND: Pancreatic stellate cells (PSCs) are precursor cells of cancer-associated fibroblasts that promote tumor proliferation, invasion, and metastasis. The glucagon-like peptide-1 receptor agonist exendin-4 has been reported to exhibit anticancer effects against several tumor cells; however, t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yan, Meizhu, Shen, Manru, Xu, Linfang, Huang, Jiying, He, Guijun, An, Min, Li, Xiaocui, Gao, Zhenjun, Meng, Xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522302/ https://www.ncbi.nlm.nih.gov/pubmed/33061431 http://dx.doi.org/10.2147/OTT.S259853

Ejemplares similares

BAG3‐positive pancreatic stellate cells promote migration and invasion of pancreatic ductal adenocarcinoma
por: Yuan, Ye, et al.
Publicado: (2019)

Pancreatic stellate cells facilitate pancreatic cancer cell viability and invasion
por: Liu, Shang-Long, et al.
Publicado: (2019)

Ion channels in control of pancreatic stellate cell migration
por: Storck, Hannah, et al.
Publicado: (2016)

Disruption of pancreatic stellate cell myofibroblast phenotype promotes pancreatic tumor invasion
por: Murray, Elizabeth R., et al.
Publicado: (2022)

Baicalin Ameliorates Pancreatic Fibrosis by Inhibiting the Activation of Pancreatic Stellate Cells in Mice with Chronic Pancreatitis
por: Fan, Jianwei, et al.
Publicado: (2021)

Role of pancreatic stellate cells in chemoresistance in pancreatic cancer
por: McCarroll, Joshua A., et al.
Publicado: (2014)

ATRA mechanically reprograms pancreatic stellate cells to suppress matrix remodelling and inhibit cancer cell invasion
por: Chronopoulos, Antonios, et al.
Publicado: (2016)

Pancreatic stellate cell: Pandora's box for pancreatic disease biology
por: Bynigeri, Ratnakar R, et al.
Publicado: (2017)

A Rising Star in Pancreatic Diseases: Pancreatic Stellate Cells
por: Xue, Ran, et al.
Publicado: (2018)

Pancreatic Stellate Cells and the Targeted Therapeutic Strategies in Chronic Pancreatitis
por: Chang, Man, et al.
Publicado: (2023)

Molecular Mechanism of Pancreatic Stellate Cells Activation in Chronic Pancreatitis and Pancreatic Cancer
por: Jin, Guihua, et al.
Publicado: (2020)

Nuclear translocation of FGFR1 and FGF2 in pancreatic stellate cells facilitates pancreatic cancer cell invasion
por: Coleman, Stacey J, et al.
Publicado: (2014)

Interaction of Stellate Cells with Pancreatic Carcinoma Cells
por: Habisch, Hansjörg, et al.
Publicado: (2010)

L-Cysteine Administration Attenuates Pancreatic Fibrosis Induced by TNBS in Rats by Inhibiting the Activation of Pancreatic Stellate Cell
por: Yang, LiJuan, et al.
Publicado: (2012)

Multivalent γ‐PGA‐Exendin‐4 Conjugates to Target Pancreatic β‐Cells
por: Rossi, Lorenzo, et al.
Publicado: (2022)

Pancreatic Stellate Cells Facilitate Perineural Invasion of Pancreatic Cancer via HGF/c-Met Pathway
por: Nan, Ligang, et al.
Publicado: (2019)

A Transcriptional Sequencing Analysis of Islet Stellate Cell and Pancreatic Stellate Cell
por: Wang, Xiaohang, et al.
Publicado: (2018)

Erratum to fibroblast activation protein α-positive pancreatic stellate cells promote the migration and invasion of pancreatic cancer by CXCL1-mediated Akt phosphorylation
Publicado: (2021)

Pancreatic cancer-derived exosomes promoted pancreatic stellate cells recruitment by pancreatic cancer
por: Zhang, Yue-Feng, et al.
Publicado: (2019)

Cinobufacini Inhibits the Development of Pancreatic Cancer Cells through the TGFβ/Smads Pathway of Pancreatic Stellate Cells
por: Li, Quan-Wang, et al.
Publicado: (2022)

Hypoxia activated HGF expression in pancreatic stellate cells confers resistance of pancreatic cancer cells to EGFR inhibition
por: Shi, Xiuhui, et al.
Publicado: (2022)

Biology of pancreatic stellate cells—more than just pancreatic cancer
por: Ferdek, Pawel E., et al.
Publicado: (2017)

Subtypes of pancreatic stellate cells and distant metastasis of pancreatic ductal adenocarcinoma
por: Fan, Yuhui, et al.
Publicado: (2020)

Pancreatic stellate cells in pancreatic cancer: as potential targets for future therapy
por: Wang, Zhengfeng, et al.
Publicado: (2023)

Molecular regulation of pancreatic stellate cell function
por: Jaster, Robert
Publicado: (2004)

Repositioning of duloxetine to target pancreatic stellate cells
por: Sagara, Akiko, et al.
Publicado: (2021)

Resveratrol Ameliorates the Malignant Progression of Pancreatic Cancer by Inhibiting Hypoxia-induced Pancreatic Stellate Cell Activation
por: Xiao, Ying, et al.
Publicado: (2020)

ITGA5 inhibition in pancreatic stellate cells attenuates desmoplasia and potentiates efficacy of chemotherapy in pancreatic cancer
por: Kuninty, Praneeth R., et al.
Publicado: (2019)

Pancreatic stellate cell secreted IL-6 stimulates STAT3 dependent invasiveness of pancreatic intraepithelial neoplasia and cancer cells
por: Nagathihalli, Nagaraj S., et al.
Publicado: (2016)

Hic-5 is required for activation of pancreatic stellate cells and development of pancreatic fibrosis in chronic pancreatitis
por: Gao, Lin, et al.
Publicado: (2020)

Impact of the secretome of activated pancreatic stellate cells on growth and differentiation of pancreatic tumour cells
por: Marzoq, Aseel J., et al.
Publicado: (2019)

Activated Pancreatic Stellate Cells Enhance the Warburg Effect to Cause the Malignant Development in Chronic Pancreatitis
por: Tao, Ye, et al.
Publicado: (2021)

Activated pancreatic stellate cells can impair pancreatic islet function in mice
por: Zang, Guangxiang, et al.
Publicado: (2015)

Cold Atmospheric Plasma Treatment for Pancreatic Cancer–The Importance of Pancreatic Stellate Cells
por: Verloy, Ruben, et al.
Publicado: (2020)

Heterogeneous Pancreatic Stellate Cells Are Powerful Contributors to the Malignant Progression of Pancreatic Cancer
por: Zhang, Zhilin, et al.
Publicado: (2021)

The context-dependent role of the Na(+)/Ca(2+)-exchanger (NCX) in pancreatic stellate cell migration
por: Loeck, Thorsten, et al.
Publicado: (2023)

Functional heterogeneity in tumor-derived human pancreatic stellate cells: Differential expression of HGF and implications for mitogenic signaling and migration in pancreatic cancer cells
por: Tjomsland, Vegard, et al.
Publicado: (2017)

The TGFβ-SMAD3 pathway inhibits IL-1α induced interactions between human pancreatic stellate cells and pancreatic carcinoma cells and restricts cancer cell migration
por: Tjomsland, Vegard, et al.
Publicado: (2016)

What are the macrophages and stellate cells doing in pancreatic adenocarcinoma?
por: Pandol, Stephen J., et al.
Publicado: (2015)

Regulation of pancreatic stellate cell activation by Notch3
por: Song, Haiyan, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_f2btnpnole52udc7t6482un0t0