A Novel Therapeutic siRNA Nanoparticle Designed for Dual-Targeting CD44 and Gli1 of Gastric Cancer Stem Cells

PURPOSE: Gastric cancer stem cells (CSCs) are important for the initiation, growth, recurrence, and metastasis of gastric cancer, due to their chemo-resistance and indefinite proliferation. Herein, to eliminate gastric CSCs, we developed novel CSC-targeting glioma-associated oncogene homolog 1 (Gli1...

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Detalles Bibliográficos
Autores principales: Yao, Hongjuan, Sun, Lan, Li, Jingcao, Zhou, Xiaofei, Li, Rui, Shao, Rongguang, Zhang, Yingge, Li, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522319/
https://www.ncbi.nlm.nih.gov/pubmed/33061365
http://dx.doi.org/10.2147/IJN.S260163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522319/
https://www.ncbi.nlm.nih.gov/pubmed/33061365
http://dx.doi.org/10.2147/IJN.S260163

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