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Enhancing efficacy of gemcitabine in pancreatic patient-derived xenograft mouse models
Gemcitabine (Gem), a nucleoside analog, is a preferred choice of treatment for pancreatic cancer (PCa) and often used in combination therapy against wide range of solid tumors. It is known to be rapidly inactivated in blood by cytidine deaminase. The objective of the study was to improve the systemi...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522377/ https://www.ncbi.nlm.nih.gov/pubmed/33015617 http://dx.doi.org/10.1016/j.ijpx.2020.100056 |