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Enhancing efficacy of gemcitabine in pancreatic patient-derived xenograft mouse models

Gemcitabine (Gem), a nucleoside analog, is a preferred choice of treatment for pancreatic cancer (PCa) and often used in combination therapy against wide range of solid tumors. It is known to be rapidly inactivated in blood by cytidine deaminase. The objective of the study was to improve the systemi...

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Detalles Bibliográficos
Autores principales: Inkoom, Andriana, Ndemazie, Nkafu, Affram, Kevin, Smith, Taylor, Zhu, Xue, Underwood, Patrick, Krishnan, Sunil, Ofori, Edward, Han, Bo, Trevino, Jose, Agyare, Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522377/
https://www.ncbi.nlm.nih.gov/pubmed/33015617
http://dx.doi.org/10.1016/j.ijpx.2020.100056