Theoretical design of novel antimalarial agents against P. falciparum strain, Dd(2) through the QSAR modeling of synthesized 2′-substituted triclosan derivatives

In an attempt to design compounds with higher antimalarial activities, quantitative structure-activity relationship (QSAR) technique was utilized in the development of a molecular model for some synthesized 2′-substituted triclosan derivatives through a hybrid of the GA-MLR method. The model was fou...

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Detalles Bibliográficos
Autores principales: Ibrahim, Zakari Ya'u, Uzairu, Adamu, Shallangwa, Gideon, Abechi, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522386/
https://www.ncbi.nlm.nih.gov/pubmed/33015389
http://dx.doi.org/10.1016/j.heliyon.2020.e05032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522386/
https://www.ncbi.nlm.nih.gov/pubmed/33015389
http://dx.doi.org/10.1016/j.heliyon.2020.e05032

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