Cargando…

Identification of P-Rex1 in the Regulation of Liver Cancer Cell Proliferation and Migration via HGF/c-Met/Akt Pathway

BACKGROUND: Rho-GTPases and their activators, guanine nucleotide exchange factors (GEFs), are increasingly being recognized as essential mediators of oncogenic signaling. Although it is known that P-Rex1, a member of the Dbl family of GEFs for the Rac small GTPase, contributes to the migration of ca...

Descripción completa

Detalles Bibliográficos
Autores principales:	Qiu, Wancheng, Chang, Yanhua, Liu, Jing, Yang, Xu, Yu, Yan, Li, Jiajia, Liang, Qing, Sun, Guangchun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522411/ https://www.ncbi.nlm.nih.gov/pubmed/33061433 http://dx.doi.org/10.2147/OTT.S265592

Ejemplares similares

P-Rex1 Cooperates With TGFβR2 to Drive Lung Fibroblast Migration in Pulmonary Fibrosis
por: Liang, Qing, et al.
Publicado: (2021)

HGF/c-Met signaling promotes the migration and proliferation of deer antler MSCs
por: Wang, Miao, et al.
Publicado: (2023)

Pre-Osteoblasts Stimulate Migration of Breast Cancer Cells via the HGF/MET Pathway
por: Vallet, Sonia, et al.
Publicado: (2016)

Quercetin inhibits HGF/c-Met signaling and HGF-stimulated melanoma cell migration and invasion
por: Cao, Hui-Hui, et al.
Publicado: (2015)

HGF–Met Pathway in Regeneration and Drug Discovery
por: Matsumoto, Kunio, et al.
Publicado: (2014)

The role of HGF/c-MET signaling pathway in lymphoma
por: Lam, Bao Quoc, et al.
Publicado: (2016)

Role and Therapeutic Targeting of the HGF/MET Pathway in Glioblastoma
por: Cruickshanks, Nichola, et al.
Publicado: (2017)

HGF and c-Met Interaction Promotes Migration in Human Chondrosarcoma Cells
por: Tsou, Hsi-Kai, et al.
Publicado: (2013)

HGF/c-Met: A Key Promoter in Liver Regeneration
por: Zhao, Yang, et al.
Publicado: (2022)

Role of HGF/c‐Met in the treatment of colorectal cancer with liver metastasis
por: Yao, Jian‐feng, et al.
Publicado: (2019)

Simultaneous Inhibition of the HGF/MET and Erk1/2 Pathways Affect Uveal Melanoma Cell Growth and Migration
por: Chattopadhyay, Chandrani, et al.
Publicado: (2014)

Targeting the HGF/c-MET pathway: stromal remodelling in pancreatic cancer
por: Pothula, Srinivasa P., et al.
Publicado: (2017)

SMYD3 Modulates the HGF/MET Signaling Pathway in Gastric Cancer
por: De Marco, Katia, et al.
Publicado: (2023)

The zebrafish HGF receptor met controls migration of myogenic progenitor cells in appendicular development
por: Nord, Hanna, et al.
Publicado: (2019)

Adipose-Derived Stem Cells Promote Proliferation and Invasion in Cervical Cancer by Targeting the HGF/c-MET Pathway
por: Zhai, Yongning, et al.
Publicado: (2020)

HGF-MET as a breast cancer biomarker
por: Liu, Shuying
Publicado: (2015)

HGF/c-MET Signaling in Melanocytes and Melanoma
por: Czyz, Malgorzata
Publicado: (2018)

HGF/Met Axis in Heart Function and Cardioprotection
por: Gallo, Simona, et al.
Publicado: (2014)

Physiological Signaling and Structure of the HGF Receptor MET
por: Baldanzi, Gianluca, et al.
Publicado: (2014)

HGF/MET Signaling in Malignant Brain Tumors
por: Mulcahy, Elizabeth Qian Xu, et al.
Publicado: (2020)

Peroxisome Proliferator-Activated Receptor gamma negatively regulates liver regeneration after partial hepatectomy via the HGF/c-Met/ERK1/2 pathways
por: Cheng, Zhangjun, et al.
Publicado: (2018)

The HGF-MET axis coordinates liver cancer metabolism and autophagy for chemotherapeutic resistance
por: Huang, Xing, et al.
Publicado: (2019)

MET/HGF Signaling Pathway in Ovarian Carcinoma: Clinical Implications and Future Direction
por: Mhawech-Fauceglia, Paulette, et al.
Publicado: (2012)

Cooperative interaction of MUC1 with the HGF/c-Met pathway during hepatocarcinogenesis
por: Bozkaya, Giray, et al.
Publicado: (2012)

Mechanistically detailed systems biology modeling of the HGF/Met pathway in hepatocellular carcinoma
por: Jafarnejad, Mohammad, et al.
Publicado: (2019)

HGF-independent Potentiation of EGFR Action by c-Met
por: Dulak, Austin M., et al.
Publicado: (2011)

Targeting the HGF-cMET Axis in Hepatocellular Carcinoma
por: Venepalli, Neeta K., et al.
Publicado: (2013)

HGF/MET and the Immune System: Relevance for Cancer Immunotherapy
por: Papaccio, Federica, et al.
Publicado: (2018)

Cyclic Peptide-Based Biologics Regulating HGF-MET
por: Sato, Hiroki, et al.
Publicado: (2020)

The Function of the HGF/c-Met Axis in Hepatocellular Carcinoma
por: Wang, Haiyu, et al.
Publicado: (2020)

Targeting HGF/c-MET Axis in Pancreatic Cancer
por: Pothula, Srinivasa P., et al.
Publicado: (2020)

The Role of HGF/MET Signaling in Metastatic Uveal Melanoma
por: Tanaka, Ryota, et al.
Publicado: (2021)

HGF and MET: From Brain Development to Neurological Disorders
por: Desole, Claudia, et al.
Publicado: (2021)

MicroRNA-182 Suppresses HGF/SF-Induced Increases in Retinal Pigment Epithelial Cell Proliferation and Migration through Targeting c-Met
por: Wang, Lihua, et al.
Publicado: (2016)

Mitogen-inducible gene 6 is an endogenous inhibitor of HGF/Met-induced cell migration and neurite growth
por: Pante, Guido, et al.
Publicado: (2005)

The potential roles of hepatocyte growth factor (HGF)-MET pathway inhibitors in cancer treatment
por: Parikh, Rahul A, et al.
Publicado: (2014)

Deguelin suppresses angiogenesis in human hepatocellular carcinoma by targeting HGF-c-Met pathway
por: Li, Ming, et al.
Publicado: (2017)

Extracellular Matrix Influencing HGF/c-MET Signaling Pathway: Impact on Cancer Progression
por: Noriega-Guerra, Heydi, et al.
Publicado: (2018)

Structural and Functional Insight Into the Glycosylation Impact Upon the HGF/c-Met Signaling Pathway
por: Hu, Xinyue, et al.
Publicado: (2020)

Pancreatic Stellate Cells Facilitate Perineural Invasion of Pancreatic Cancer via HGF/c-Met Pathway
por: Nan, Ligang, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_68jb8thpuje2qiau3k2jmp2b9d