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Successful free flap salvage surgery with off-label use of Alteplase: A case report, review of the literature and our free flap salvage algorithm

INTRODUCTION: Microvascular free tissue transfer is a technique for reconstruction of large defects in head and neck surgery. Failure due to microvascular thrombosis can lead to microvascular damage or flap loss. Recombinant tissue-type plasminogen activator (Alteplase) is still an off-label use but...

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Detalles Bibliográficos
Autores principales: Barhoum, Fatima, Tschaikowsky, Klaus, Koch, Michael, Kapsreiter, Markus, Sievert, Matti, Müller, Sarina, Goncalves, Miguel, Traxdorf, Maximilian, Scherl, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522445/
https://www.ncbi.nlm.nih.gov/pubmed/32998058
http://dx.doi.org/10.1016/j.ijscr.2020.09.035