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Ribosylation induced structural changes in Bovine Serum Albumin: understanding high dietary sugar induced protein aggregation and amyloid formation

Non-enzymatic glycation of proteins is believed to be the root cause of high dietary sugar associated pathophysiological maladies. We investigated the structural changes in protein during progression of glycation using ribosylated Bovine Serum Albumin (BSA). Non enzymatic attachment of about 45 ribo...

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Detalles Bibliográficos
Autores principales: Das, Ahana, Basak, Pijush, Pramanik, Arnab, Majumder, Rajib, Ghosh, Avishek, Hazra, Saugata, Guria, Manas, Bhattacharyya, Maitree, Banik, Samudra Prosad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522498/
https://www.ncbi.nlm.nih.gov/pubmed/33015393
http://dx.doi.org/10.1016/j.heliyon.2020.e05053